Bruker Pharmascan 7T system

Capabilities

  • Designed for small animal imaging (mouse & rat)
  • ‘Conventional’ MR images based on T1, T2 or proton density. These are used to show anatomical detail.
  • Blood flow in arteries or veins (magnetic resonance angiography or MRA)
  • Blood perfusion through tissue, giving cerebral blood flow and cerebral blood volume maps
  • Blood volume in tissue using contrast agents
  • Molecular diffusion of water through tissue such as white matter tracts (tractography and diffusion tensor imaging or DTI)
  • Relative degrees of bound and unbound water (magnetisation transfer contrast or MTC)
  • Tissue movement, such as motion of the heart to yield measures of ejection fraction and myocardial wall motion
  • Tissue temperature
  • fMRI: Oxygenation of blood (BOLD) to show areas of brain activated by stimuli
  • fMRI: cerebral blood volume changes
  • resting-state fMRI
  • Changes in blood perfusion through tissues in response to pharmacological intervention (phMRI)
  • Intracellular pH of tissue