BioSpec 70/30 7T MRI scanner

BioSpec MRI Scanner

Bruker BioSpec Avance IIIHD 7T  Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy (MRS) system

7T (300 MHz), 30 cm bore size

Gradient inserts for rat and mouse

Equipped for X-nuclei MR

Capabilities

The system can be used to non-invasively produce many different types of images in animals up to the size of a rabbit. These include:

  • ‘Conventional’ MR images based on T1, T2 or proton density. These are used to show anatomical detail.
  • Blood flow in arteries or veins (magnetic resonance angiography or MRA)
  • Blood perfusion through tissue, giving cerebral blood flow and cerebral blood volume maps
  • Blood volume in tissue using contrast agents
  • Molecular diffusion of water through tissue such as white matter tracts (tractography and diffusion tensor imaging or DTI)
  • Relative degrees of bound and unbound water (magnetisation transfer contrast or MTC)
  • Tissue movement, such as motion of the heart to yield measures of ejection fraction and myocardial wall motion
  • Tissue temperature
  • fMRI: Oxygenation of blood (BOLD) to show areas of brain activated by stimuli
  • fMRI: cerebral blood volume changes
  • resting-state fMRI
  • Changes in blood perfusion through tissues in response to pharmacological intervention (phMRI)
  • Spectroscopy and spectroscopic imaging
  • Intracellular pH of tissue
  • Fluorine (19F) MRI